<p>The present invention is related to pyridinyl acetonitriles as well as to pharmaceutical formulations containing such pyridinyl acetonitriles. Said pyridinyl acetonitriles are modulators of the protein kinase signalling pathways, particularly the one involving Glycogen Kinase Synthase 3 or JNK. The present invention is furthermore related to methods of preparing pyridinyl acetonitriles. X is a substituted or unsubstituted pyridinyl. G is an unsubstituted or substituted pyrimidinyl or triazinyl.</p>
申请公布号
WO2004098607(A1)
申请公布日期
2004.11.18
申请号
WO2004EP04808
申请日期
2004.05.03
申请人
APPLIED RESEARCH SYSTEMS ARS HOLDING N. V.;SCHWARZ, MATTHIAS;GAILLARD, PASCALE;GOTTELAND, JEAN-PIERRE;THOMAS, RUSSELL, J.;PAGE, PATRICK
发明人
SCHWARZ, MATTHIAS;GAILLARD, PASCALE;GOTTELAND, JEAN-PIERRE;THOMAS, RUSSELL, J.;PAGE, PATRICK