| 发明名称 |
2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS |
| 摘要 |
<p>A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X is CFH, or CF<2#191, R¿1? is the moiety represented by the formula: [wherein R¿2? is (lower)alkyl, R¿3? is phenyl-(lower)alkyl, and the like.], and the like.] Compounds of formula (I) inhibit DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.</p> |
| 申请公布号 |
WO2004099185(A1) |
申请公布日期 |
2004.11.18 |
| 申请号 |
WO2004JP06568 |
申请日期 |
2004.05.10 |
| 申请人 |
FUJISAWA PHARMACEUTICAL CO. LTD.;SHIMA, ICHIRO;KUROSAKI, TOSHIO;WADA, AIKO |
发明人 |
SHIMA, ICHIRO;KUROSAKI, TOSHIO;WADA, AIKO |
| 分类号 |
C07D207/16;C07D401/12;C07D403/12;C07D409/12;C07D417/12;(IPC1-7):C07D401/12;A61K31/402 |
主分类号 |
C07D207/16 |
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