发明名称 Methods of treating p38 kinase-associated conditions with pyrrolotriazine compounds
摘要 Methods of treating one or more conditions associated with p38 kinase activity are disclosed comprising administering to a patient in need thereof at least one compound having the formula (I): or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R3 is hydrogen, methyl, perfluoromethyl, methoxy, halogen, cyano, or NH2, preferably methyl, and X, R1 through R6, and Z are as described in the specification. Advantageously the groups -ZR4R5 taken together comprise an -NH-substituted aryl.
申请公布号 US2004229877(A1) 申请公布日期 2004.11.18
申请号 US20030696178 申请日期 2003.10.29
申请人 LEFTHERIS KATERINA;HYNES JOHN;WROBLESKI STEPHEN T.;BARRISH JOEL 发明人 LEFTHERIS KATERINA;HYNES JOHN;WROBLESKI STEPHEN T.;BARRISH JOEL
分类号 A61P11/06;A61P19/02;A61P19/10;C07D207/50;C07D487/04;C07D519/00;(IPC1-7):A61K31/53 主分类号 A61P11/06
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