发明名称 |
BETA-ENDORPHIN / CRF - GENE THERAPY FOR COMBATTING PAIN LOCALLY |
摘要 |
<p>A remedy to suppress the sensation of pain, especially in chronic inflammatory diseases, by means of expressing endogenous neuroendocrine peptides at the site of inflammation. In particular, the invention relates to the expression of POMC or CRF from locally injected DNA expression constructs, preferably covalently peptide-modified expression constructs.</p> |
申请公布号 |
EP1363658(B1) |
申请公布日期 |
2004.11.17 |
申请号 |
EP20020714031 |
申请日期 |
2002.02.19 |
申请人 |
MOLOGEN AG |
发明人 |
WITTIG, BURGHARDT;STEIN, CHRISTOPH;SCHAEFER, MICHAEL;SCHROFF, MATTHIAS;JUNGHANS, CLAAS;KOENIG MEREDIZ, SVEN ANDRES |
分类号 |
A61K38/00;A61K38/33;A61K38/35;A61K48/00;A61P29/00;C07K14/575;C07K14/665;C07K14/675;C07K14/69;C07K14/695;(IPC1-7):A61K38/33 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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