发明名称 |
Intermediates for synthesis of vinblastine compound and method for synthesizing the intermediate |
摘要 |
Intermediates A, which are important in the whole synthesis of vindoline; and a method of synthesizing intermediates respectively represented by the general formulae B and C. By the method, the target intermediates are effectively synthesized with satisfactory reproducibility. This synthesis method is especially suitable for mass production. General formula A General formula B General formula C.
|
申请公布号 |
US6818777(B2) |
申请公布日期 |
2004.11.16 |
申请号 |
US20030380831 |
申请日期 |
2003.03.19 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
FUKUYAMA TOHRU;TOKUYAMA HIDETOSHI |
分类号 |
C07D405/12;(IPC1-7):C07D209/12;C07D217/08;C07D215/12;A61K31/47;A61K31/404;A61K31/18;C07C311/08 |
主分类号 |
C07D405/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|