发明名称 Intermediates for synthesis of vinblastine compound and method for synthesizing the intermediate
摘要 Intermediates A, which are important in the whole synthesis of vindoline; and a method of synthesizing intermediates respectively represented by the general formulae B and C. By the method, the target intermediates are effectively synthesized with satisfactory reproducibility. This synthesis method is especially suitable for mass production. General formula A General formula B General formula C.
申请公布号 US6818777(B2) 申请公布日期 2004.11.16
申请号 US20030380831 申请日期 2003.03.19
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 FUKUYAMA TOHRU;TOKUYAMA HIDETOSHI
分类号 C07D405/12;(IPC1-7):C07D209/12;C07D217/08;C07D215/12;A61K31/47;A61K31/404;A61K31/18;C07C311/08 主分类号 C07D405/12
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