发明名称 |
2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids |
摘要 |
A compound having the formula:wherein, R1 represents 2'-O-alkylthioalkyl or 2'-C-alkylthioalkyl; X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.
|
申请公布号 |
US6818759(B2) |
申请公布日期 |
2004.11.16 |
申请号 |
US20020174850 |
申请日期 |
2002.06.19 |
申请人 |
SIRNA THERAPEUTICS, INC. |
发明人 |
BEIGELMAN LEONID;KARPEISKY ALEX |
分类号 |
C07H19/06;C07H19/10;C07H19/16;C07H19/20;C07H21/00;C12N15/113;(IPC1-7):C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
C07H19/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|