发明名称 |
Substances K97-0239 and process for producing the same |
摘要 |
A microorganism capable of producing substances K97-0239 comprising K97-0239A represented by the following formula [I]: and K97-0239B represented by the following formula [II]: is cultured in a medium and the substances K97-0239 thus accumulated in the medium are collected from the culture medium. The obtained substances have a low toxicity and specifically inhibit the foaming of macrophages. Owing to these characteristics, they are useful in preventing and treating human arteriosclerosis and diseases caused thereby.
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申请公布号 |
US6818422(B2) |
申请公布日期 |
2004.11.16 |
申请号 |
US20030398578 |
申请日期 |
2003.10.01 |
申请人 |
GAKKOU HOUJIN KITASATO GAKUEN;JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE |
发明人 |
OMURA SATOSHI;TOMODA HIROSHI |
分类号 |
A61K38/00;C07K5/02;C07K7/54;(IPC1-7):C12P17/18;C12N1/20;C07D489/00;C07D487/02;C07D487/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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