DISUBSTITUTED ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY

摘要

Monocyclic and bicyclic aryl ring compounds having selective LTB4 antagonist properties and comprising two ring substituents, the first substituent comprising a lipophilic group and a terminal carboxylic acid or derivative group, and the second substituent comprising an amido group, therapeutic compositions and methods of treatment of disorders which result from LTB4 activity using the mono- and bicyclic. aryl compounds are disclose d.