| 发明名称 |
AUTOLOGOUS CANCER CELL VACCINE |
| 摘要 |
An autologous cancer cell vaccine comprises cancer cells that express both MHCI and MHCII on their cell surface. The MHCI presents a cancer antigen and the MHCII presents a non-self antigen. |
| 申请公布号 |
US2016228524(A1) |
申请公布日期 |
2016.08.11 |
| 申请号 |
US201615132827 |
申请日期 |
2016.04.19 |
| 申请人 |
Kreutz Fernando Thome |
发明人 |
Kreutz Fernando Thome |
| 分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for making isolated immunogenic cancer cells or an immunogenic extract thereof comprising both MHCI and MHCII, the method comprising:
inducing expression of MHCII on cancer cells isolated from a subject; incubating the cancer cells with a non-self antigen so that the non-self antigen will be bound to expressed MHCII; and killing the cancer cells. |
| 地址 |
Porto Alegre - RS BR |
