发明名称 Dry Formulations of Vaccines That Are Room Temperature Stable
摘要 The present invention discloses dry formulations of room temperature stable vaccines that comprise a live attenuated virus, a sugar stabilizer, and an amino acid stabilizer. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines.
申请公布号 US2016228369(A1) 申请公布日期 2016.08.11
申请号 US201415024226 申请日期 2014.09.26
申请人 Intervet International B.V. ;Intervet Inc. 发明人 Qiao Zhisong;O'Connell Kevin
分类号 A61K9/16;C12N7/00;A61K39/155;A61K39/23;A61K39/175;A61K39/235 主分类号 A61K9/16
代理机构 代理人
主权项 1. A dry formulation of a vaccine that comprises a live attenuated virus, 30% to 80% (w/w) of a non-reducing oligosaccharide, 5% to 40% (w/w) of an amino acid stabilizer, 2% to 20% (w/w) of a protein stabilizer, and a buffer having a pH of 6.0 to 8.0.
地址 Boxmeer NL