发明名称 |
Dry Formulations of Vaccines That Are Room Temperature Stable |
摘要 |
The present invention discloses dry formulations of room temperature stable vaccines that comprise a live attenuated virus, a sugar stabilizer, and an amino acid stabilizer. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines. |
申请公布号 |
US2016228369(A1) |
申请公布日期 |
2016.08.11 |
申请号 |
US201415024226 |
申请日期 |
2014.09.26 |
申请人 |
Intervet International B.V. ;Intervet Inc. |
发明人 |
Qiao Zhisong;O'Connell Kevin |
分类号 |
A61K9/16;C12N7/00;A61K39/155;A61K39/23;A61K39/175;A61K39/235 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
1. A dry formulation of a vaccine that comprises a live attenuated virus, 30% to 80% (w/w) of a non-reducing oligosaccharide, 5% to 40% (w/w) of an amino acid stabilizer, 2% to 20% (w/w) of a protein stabilizer, and a buffer having a pH of 6.0 to 8.0. |
地址 |
Boxmeer NL |