发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING THE INTERACTION BETWEEN ADIPONECTIN AND ITS RECEPTOR |
摘要 |
The invention is directed to methods for identifying agents that mimic or modulate the interaction between adiponectin and its receptor. In particular, the invention is directed to methods for mimicking or modulating the adiponectin-T-cadherin interaction in order to treat diseases and disorders associated with a deficiency or overabundance of adiponectin. Such diseases include, e.g., obesity, anorexia nervosa, type I and type II diabetes, coronary artery disease and atherosclerosis. The invention also provides isolated adiponectin-T-cadherin complexes and methods for identifying polypeptides that interact with adiponectin. |
申请公布号 |
WO2004096272(A2) |
申请公布日期 |
2004.11.11 |
申请号 |
WO2004EP04473 |
申请日期 |
2004.04.28 |
申请人 |
CYTOS BIOTECHNOLOGY AG;SAUDAN, PHILIPPE;BACHMANN, MARTIN |
发明人 |
SAUDAN, PHILIPPE;BACHMANN, MARTIN |
分类号 |
C07K14/47;C07K14/705;G01N33/566 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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