METHOD FOR PRODUCING SOLID GALENIC FORMULATIONS USING A CROSSLINKED NON-THERMOPLASTIC CARRIER

摘要

The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing agents, c) 0.1 to 49.5 wt. % of at least one active principle, at a temperature not less than the softening temperature of the adjuvant but rising to at least 70 DEG C; then in cooling the resulting paste. Said solid galenic formulations quickly disintegrate in an aqueous medium.