| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for inducing the change of the spiral structure of a double-stranded DNA with a polycarbazole derivative and an acid without adding a high concentration acid or an alcohol to the aqueous solution of the double-stranded DNA, and a method for utilizing the same, and the like. SOLUTION: The method for inducing the change of the spiral structure of the double-stranded DNA is characterized by having a process for mixing the double-stranded DNA, a polycarbazole derivative and a substance for receiving an electron from the polycarbazole derivative. Thereby, the spiral structure of the double-stranded DNA can be changed, for example, from a B type DNA structure to a Z type DNA structure. The method for inducing the change of the spiral structure of the double-stranded DNA can be applied to a DNA switching system, a method for detecting a specific base sequence, and the like. COPYRIGHT: (C)2005,JPO&NCIPI
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