发明名称 |
VERFAHREN ZUR UNTERSTÜTZUNG DER DIAGNOSE DER ALZHEIMERSCHEN KRANKHEIT DURCH MESSUNG DER AMYLOID-BETA-PEPTIDE(X GROESSER ALS ODER GLEICH 41) UND TAU |
摘要 |
This invention provides methods useful in aiding in the diagnosis of Alzheimer's disease. The methods involve measuring the amount of amyloid- beta peptide (x-≥41) in the cerebrospinal fluid of a patient. High levels of the peptide generally are inconsistent with a diagnosis of Alzheimer's. Low levels of the peptide are consistent with the disease and, with other tests, can provide a positive diagnosis. Other methods involve measuring the amounts of both A beta (x-≥41) and tau. Low levels of A beta (x-≥41) and high levels of tau are a positive indicator of Alzheimer's disease, while high levels of A beta (x-≥41) and low levels of tau are a negative indication of Alzheimer's disease. <IMAGE> |
申请公布号 |
DE69533623(D1) |
申请公布日期 |
2004.11.11 |
申请号 |
DE1995633623 |
申请日期 |
1995.11.13 |
申请人 |
ELAN PHARMACEUTICALS, INC. |
发明人 |
SEUBERT, A.;VIGO-PELFREY, CARMEN;SCHENK, B.;BARBOUR, ROBIN |
分类号 |
G01N33/53;C07K14/47;C07K16/18;C12N15/09;G01N33/537;G01N33/542;G01N33/543;G01N33/68;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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