2-Guanidino-4-arylchinazolines as nhe-3 inhibitors

摘要

The invention relates to compounds of formula (I), where Ar=unsubstituted, or monosubstituted by R<3>, phenyl, or naphthyl; R<1>, R<2>=independently, A, OA, Hal or CF3; R<3>=A, OA, Hal, or CF3; A=1-6C alkyl and Hal=F, Cl, Br or I and the salts and solvates thereof as NHE3 inhibitors.