Tissue patches and related delivery systems and methods

摘要

Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a tissue implant imbedded in a substrate to form a first layer and a second layer of substrate on a top surface and a bottom surface of the tissue implant. A predetermined thickness of the first layer is different from a predetermined thickness of the second layer. A tissue patch may include a tissue implant imbedded in a substrate formed of a plurality of sections capable of being folded into a contracted state for endoluminal delivery to the lesion. A system for delivering a tissue implant includes a catheter having an expandable member at a distal end portion, a carrier placed around the expandable member, and the carrier configured to expand from a contracted state to an expanded state and to receive the tissue implant. The tissue implant contacts the lesion of the alimentary tract when the expandable member expands the carrier to the expandable state.