发明名称 |
EXTRACTION PROCESS FOR A PHARMACEUTICAL PRODUCT |
摘要 |
<p>A process for isolating a soluble, native collagen from a marine invertebrate, comprising the steps of: 1) treating a collagen-containing portion of the marine invertebrate with a weak acid solution in order to solubilise native collagen fibrils; 2) centrifuging the resultant slurry to remove tissue particulates; 3) adjusting the pH of the supernatant in order to precipitate collagen by addition of a base; 4) collecting the precipitated collagen; 5) resuspending the precipitated collagen; and performing buffer exchange against water using an 15 ultrafiltration membrane.</p> |
申请公布号 |
WO2004096834(A1) |
申请公布日期 |
2004.11.11 |
申请号 |
WO2004AU00574 |
申请日期 |
2004.04.30 |
申请人 |
NORIKA HOLDINGS PTY LTD;MANICKAVASAGAM, BHANU |
发明人 |
MANICKAVASAGAM, BHANU |
分类号 |
A61K38/00;A61L27/22;A61L27/24;A61L31/04;C07K1/14;C07K14/435;(IPC1-7):C07K1/14 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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