| 发明名称 |
INHIBITORS OF AKT ACTIVITY |
| 摘要 |
The present invention is directed to compounds which contain a substituted pyridine moiety which inhibit the activity of Akt, a serine/threonine protei n kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
|
| 申请公布号 |
CA2522431(A1) |
申请公布日期 |
2004.11.11 |
| 申请号 |
CA20042522431 |
申请日期 |
2004.04.20 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DUGGAN, MARK E.;BILODEAU, MARK T.;HARTNETT, JOHN C.;LINDSLEY, CRAIG W.;WU, ZHICAI;ZHAO, ZHIJIAN |
| 分类号 |
A61K;A61K31/00;A61K31/445;A61K45/06;C07D401/04;C07D401/14;C07D413/04;C07D413/14;C07D417/14;C07D487/04;C07F9/6558;(IPC1-7):A61K31/445 |
主分类号 |
A61K |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
