发明名称 COMPOUND HAVING ANTITUMOR ACTIVITY AND NEOVASCULARIZATION INHIBITORY ACTIVITY AND METHOD FOR PRODUCING THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a compound having an antitumor activity and a neovascularization inhibitory activity. SOLUTION: The compound is represented by general formula (I) (wherein, R<SP>1</SP>denotes a≥3C straight chain, a≥3C branched chain or a≥3C cycloalkyl group or an aromatic group; R<SP>2</SP>denotes a hydrogen atom, a straight chain, a branched chain or a cycloalkyl group, a straight chain, a branched chain or a cyclic acyl group or a protecting group of the hydroxy group; R<SP>3</SP>denotes a hydrogen atom, a straight chain, a branched chain or a cycloalkyl group, a straight chain, a branched chain or a cyclic acyl group or a protecting group of the hydroxy group; R<SP>4</SP>denotes a hydrogen atom, a straight chain, a branched chain or a cycloalkyl group; or an OR<SP>3</SP>and the R<SP>4</SP>together may denote an oxo group or an oxime group) or its optically active substance or a pharmaceutically acceptable salt thereof or a hydrate or a solvate thereof. COPYRIGHT: (C)2005,JPO&NCIPI
申请公布号 JP2004315373(A) 申请公布日期 2004.11.11
申请号 JP20030107647 申请日期 2003.04.11
申请人 INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH 发明人 OSADA HIROYUKI;KAKEYA HIDEAKI;HAYASHI YUJIRO;SHOJI MITSURU
分类号 C07D303/48;A61K31/336;A61K31/35;A61P9/00;A61P35/00;C07D493/22;(IPC1-7):C07D303/48 主分类号 C07D303/48
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