发明名称 CRYSTALLINE BIS[(E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO]PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOICACID]CALCIUM SALT
摘要 <p>The present invention relates to a crystalline form of the compound bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl) amino] pyrimidin-5-yl] (3R, 5S)-3, 5-dihydroxyhept-6-enoic acid]calcium salt, as well as processes for its manufacture and pharmaceutical compositions comprising the crystalline form, which is useful as an agent for treating hyperlipidemia, hypercholesterolemia and atherosclerosis.</p>
申请公布号 EP1144389(B1) 申请公布日期 2004.11.10
申请号 EP19990962471 申请日期 1999.12.23
申请人 ASTRAZENECA AB 发明人 TAYLOR, NIGEL, PHILLIP
分类号 A61K31/505;A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07D239/42;(IPC1-7):C07D239/42 主分类号 A61K31/505
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