发明名称 |
IMPROVED METHOD FOR THE DETECTION OF CREATININE |
摘要 |
Disclosed is an improvement to the assay for creatinine in fluid test samples by contacting the test sample with a reagent formulation containing cupric ions, a hydroperoxide and an oxidizable dye. The improvement involves the inclusion of one or more selected quinolines in the reagent formulation. When the quinoline is substituted with methyl in the 2-5 position and/or a methoxy in the 2-6 position auto-oxidation of the oxidizable dye is reduced. When the quinoline is further substituted in an otherwise unsubstituted carbon atom in the 2-8 position, the assay's resistance to interference from hemoglobin and ascorbate is increased. |
申请公布号 |
CA2281166(C) |
申请公布日期 |
2004.11.09 |
申请号 |
CA19992281166 |
申请日期 |
1999.08.25 |
申请人 |
BAYER CORPORATION |
发明人 |
CAST, TODD K.;PUGIA, MICHAEL J. |
分类号 |
G01N33/493;G01N33/52;G01N33/70;(IPC1-7):G01N33/70 |
主分类号 |
G01N33/493 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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