发明名称 |
Novel heterodimeric fusion proteins |
摘要 |
The present invention relates to the production of bispecific or multispecific, bi- or tetravalent antibodies using recombinant DNA methods and recombinant production methods. The resulting antibody consists of one or two diabody molecules that are heterodimerized by creating a fusion protein with the CL and CH1 immunoglobulin constant domains. |
申请公布号 |
US2004220388(A1) |
申请公布日期 |
2004.11.04 |
申请号 |
US20020312923 |
申请日期 |
2002.12.27 |
申请人 |
MERTENS NICO;GROOTEN JOHAN |
发明人 |
MERTENS NICO;GROOTEN JOHAN |
分类号 |
A61K39/395;A61P7/02;A61P31/00;A61P35/00;A61P37/00;C07K16/00;C07K16/46;C12N15/62;(IPC1-7):C07K16/30 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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