| 发明名称 |
MODULATION OF APOLIPOPROTEIN C-III EXPRESSION |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expressi on of apolipoprotein C-III. The compositions comprise oligonucleotides, targete d to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosi s and treatment of disease associated with expression of apolipoprotein C-III are provided. |
| 申请公布号 |
CA2522560(A1) |
申请公布日期 |
2004.11.04 |
| 申请号 |
CA20042522560 |
申请日期 |
2004.04.15 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE, ROSANNE M.;GRAHAM, MARK J.;DOBIE, KENNETH W.;LEMONIDIS TARBET, KRISTINA M. |
| 分类号 |
C07H21/00;A61K31/7088;A61K38/00;A61K48/00;A61P3/00;A61P3/04;A61P3/10;C12N15/113 |
主分类号 |
C07H21/00 |
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