发明名称 PROCESS FOR THE PREPARATION OF GABAPENTIN FORM-II
摘要 The present invention relates to a new industrial feasible process for the preparation of Gabapentin Form-II via a novel intermediate Gabapentin hemisulphate hemihydrate with out forming Gabapentin Form-III by neutralizing the Gabapentin hemisulphate hemihydrate solution with a base at higher temperatures followed by cooling to yield Gabapentin Form II with sulphate ions less than 100 ppm with respect to Gabapentin.
申请公布号 WO2004093780(A2) 申请公布日期 2004.11.04
申请号 WO2004IN00102 申请日期 2004.04.16
申请人 MATRIX LABORATORIES LTD;CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;INDUKURI, VENKATA, SUNIL, KUMAR 发明人 CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;INDUKURI, VENKATA, SUNIL, KUMAR
分类号 A61K;C07C227/04;C07C227/06;C07C227/40;C07C227/42;C07C229/28 主分类号 A61K
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