| 发明名称 |
TRICYCLIC INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER`S DISEASE |
| 摘要 |
The present invention relates to novel hydroxyethylamine compounds having As p2 (.beta.-secretase, BACE1 or Memapsin) inhibitory activity, processes for the ir preparation, to compositions containing them and to their use in the treatme nt of diseases characterised by elevated .beta.- amyloid levels or .beta.-amylo id deposits, particularly Alzheimer's disease.
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| 申请公布号 |
CA2523291(A1) |
申请公布日期 |
2004.11.04 |
| 申请号 |
CA20042523291 |
申请日期 |
2004.04.21 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
REDSHAW, SALLY;DEMONT, EMMANUEL HUBERT;WALTER, DARYL SIMON |
| 分类号 |
C07D487/06;C07D513/06;(IPC1-7):C07D487/14;A61K31/55;A61K31/554 |
主分类号 |
C07D487/06 |
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