MAGNETICALLY CONTROLLABLE DRUG AND GENE DELIVERY STENTS

摘要

Magnetizable implantable devices and methods for their use in delivery of therapeutic agents encapsulated or dispersed in a magnetic carrier to a selected site of implantation in a subject are provided. In one embodiment, the device includes a magnetizable stent where segments of the magnetizable compound have been electro-deposited on some of the struts of the stent. Blood flow through the artery brings the therapeutic agent in a magnetic carrier in proximity within the implanted stent. As blood flows through the stent, the therapeutic agent in the magnetic carrier is attracted to the segments of the stent with the magnetizable compound.