发明名称 |
Nonspecific hydridization inhibitors, clinical examination reagents and clinical examination method |
摘要 |
The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.
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申请公布号 |
US2004219546(A1) |
申请公布日期 |
2004.11.04 |
申请号 |
US20040476069 |
申请日期 |
2004.02.11 |
申请人 |
SAKAKI SHUJIRO;SHUTO KENSHIRO;TSUCHIDA MAMORU;ASHIHARA YOSHIHIRO;ISOMURA MITSUO |
发明人 |
SAKAKI SHUJIRO;SHUTO KENSHIRO;TSUCHIDA MAMORU;ASHIHARA YOSHIHIRO;ISOMURA MITSUO |
分类号 |
C08F30/02;C08F230/02;C08L43/00;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C08F30/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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