发明名称 PROCESS FOR THE PREPARATION OF GABAPENTIN FORM-II
摘要 The present invention relates to a new industrial feasible process for the preparation of Gabapentin Form-II by converting the Gabapentin hydrochloride salt directly into Form-II without the formation of Form-III by neutralizing the Gabapentin hydrochloride solution with a base at higher temperatures followed by cooling to yield Gabapentin Form-II with chloride ions less than 100 ppm with respect to Gabapentin.
申请公布号 WO2004093779(A2) 申请公布日期 2004.11.04
申请号 WO2004IN00101 申请日期 2004.04.16
申请人 MATRIX LABORATORIES LTD;CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;INDUKURI, VENKATA, SUNIL, KUMAR;SIMHADRI, SRINIVAS 发明人 CHAVA, SATYANARAYANA;GORANTLA, SEETA, RAMANJANEYULU;INDUKURI, VENKATA, SUNIL, KUMAR;SIMHADRI, SRINIVAS
分类号 A61K;C07C227/06;C07C229/28 主分类号 A61K
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