发明名称 |
THE USE OF YOP PREOTEINS OR RHO GTPASE INHIBITORS AS CASPASE-1 INHIBITORS |
摘要 |
The present invention relates to the use of Yops as caspase inhibitors. More specifically, it relates to the use of YopE and YopT as inhibitors of caspase-1 activity. The inhibitor can be used to treat caspase-1-related pathologies, such as inflammatory diseases and to inhibit caspase-1-related and/or -mediated cell death. |
申请公布号 |
WO2004064713(A3) |
申请公布日期 |
2004.11.04 |
申请号 |
WO2004EP50026 |
申请日期 |
2004.01.20 |
申请人 |
VIB VZW;UNIV GENT;BEYAERT RUDI;SCHOTTE PETER |
发明人 |
BEYAERT RUDI;SCHOTTE PETER |
分类号 |
A61K;A61K38/16;A61K38/45;A61K38/47;A61P1/00;A61P25/28;C07K14/24 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|