MAGNETICALLY CONTROLLABLE DRUG AND GENE DELIVERY STENTS

摘要

Magnetizable implantable devices and methods for their use in delivery of therapeutic agents encapsulated or dispersed in a magnetic carrier to a selected site of implantation in a subject are provided. In one embodiment, the device includes a magnetizable stent where segments of the magnetizable compound have been electro-deposited on some of the struts of the stent. Blo od flow through the artery brings the therapeutic agent in a magnetic carrier i n proximity within the implanted stent. As blood flows through the stent, the therapeutic agent in the magnetic carrier is attracted to the segments of th e stent with the magnetizable compound.