发明名称 |
MODIFIED TRANSFERRIN FUSION PROTEINS COMPRISING DUPLICATE TRANSFERRIN AMINO OR CARBOXY TERMINAL DOMAINS |
摘要 |
Fusion proteins of transferrin and other therapeutic moieties with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. |
申请公布号 |
WO2004020454(A3) |
申请公布日期 |
2004.11.04 |
申请号 |
WO2003US26742 |
申请日期 |
2003.08.28 |
申请人 |
BIOREXIS PHARMACEUTICAL CORPORATION;TURNER, ANDREW, J.;SADEGHI, HOMAYOUN |
发明人 |
TURNER, ANDREW, J.;SADEGHI, HOMAYOUN |
分类号 |
A61K38/00;A61K47/48;C07K7/06;C07K7/08;C07K14/705;C07K14/79 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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