Novel anti-inflammatory androstane derivative compositions

摘要

There is provided a crystalline chemical composition comprising a compound of formula (I) in which the crystal lattice is stabilised by the presence of a guest molecule, characterised in the crystalline composition is of space group P212121 having unit cell dimensions of about 7.6±0.6 Å, 12.7±0.7 Å, and 33±3 Å when determined at 120K, wherein at about 295K said composition exhibits one or more of the following XRPD profiles: (i) a peak in the range of around 4.3-5.0; (ii) a peak in the range of around 6.6-6.9; or (iii) a peak in the range of around 11.5-11.8.