发明名称 |
PROCESS FOR PREPARING 4,17(20)-PROSTADIEN-3,16-DIONE FROM 16 ALPHA, 17 ALPHA-EPOXYPREGNENOLONE AND INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME FOR A SHORT REACTION TIME WITH HIGH EFFICIENCY |
摘要 |
<p>PURPOSE: A process for preparing 4,17(20)-prostadien-3,16-dione from 16 alpha, 17 alpha-epoxypregnenolone are provided to effectively lower the values for low density lipoprotein and cholesterol and to increase the value for high density lipoprotein. CONSTITUTION: The process for preparing 4,17(20)-prostadien-3,16-dione(E-guggulsterone) represented by formula III from 16 alpha, 17 alpha-epoxypregnenolone comprises the steps of: reacting 16 alpha, 17 alpha-epoxypregnenolone represented by formula I with a hydrazine to obtain a compound represented by formula II, wherein 1 to 40 equivalent of the hydrazine is used to the 16 alpha, 17 alpha-epoxypregnenolone; and then oxidizing it using aluminum alkoxides.</p> |
申请公布号 |
KR20040092066(A) |
申请公布日期 |
2004.11.03 |
申请号 |
KR20030025904 |
申请日期 |
2003.04.24 |
申请人 |
KANG, HEON JOONG |
发明人 |
HAM, JEONG YEOP;JIN, JEONG UK;KANG, HEON JOONG |
分类号 |
C07J13/00;(IPC1-7):C07J13/00 |
主分类号 |
C07J13/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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