| 发明名称 |
CYCLOSPORIN A DERIVATIVES MODIFIED AT POSITION 1 AND FLUORESCENCE POLARIZATION ASSAY FOR CYCLOSPORIN A AND METABOLITES |
| 摘要 |
The present invention is directed to a fluorescence polarization immunoassay for cyclosporin A and metabolites thereof. The present invention also relates to novel cyclosporin A derivative compounds useful in fluorescence polarization techniques. Included among the novel compounds are cyclosporin A derivatives where the amino acid in the first position is altered. The cyclosporin A derivatives are useful in forming immunogens for raising antibodies specific to cyclosporin A and metabolites thereof.
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| 申请公布号 |
CA1341463(C) |
申请公布日期 |
2004.11.02 |
| 申请号 |
CA19880562525 |
申请日期 |
1988.03.25 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
WANG, PHILIP P.;MORRISON, MARJORIE ANNE;WANG, NAI-YI |
| 分类号 |
G01N33/53;C07K7/64;C07K16/12;C07K19/00;G01N33/542;G01N33/68;G01N33/94;(IPC1-7):C07K7/64;A61P37/06;A61K38/13;G01N33/533;G01N33/58;G01N21/64 |
主分类号 |
G01N33/53 |
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