发明名称 |
Prevention and treatment of degenerative diseases by glutathione and phase II detoxification enzymes |
摘要 |
The present invention generally relates to the field of treating degenerative disease by administering a pharmaceutically effective amount of a compound that elevates glutathione or at least one Phase II detoxification enzyme in diseased tissue. The present invention also relates to a pharmaceutical composition useful for the treatment of degenerative diseases, as well as a method of identifying agents that modulate intracellular levels of glutathione or intracellular levels of at least one Phase II enzyme in neuronal cells.
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申请公布号 |
US6812248(B2) |
申请公布日期 |
2004.11.02 |
申请号 |
US20010897934 |
申请日期 |
2001.07.05 |
申请人 |
JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
ZHANG YUESHENG;HO TONY W.;LI YUN |
分类号 |
A61K31/05;A61K31/085;A61K31/194;A61K31/198;A61K31/26;A61K31/497;A61P25/28;(IPC1-7):A61K31/21 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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