发明名称 |
Vector for oral administration of pharmaceuticals, useful particularly for delivering insulin or vaccines, comprises hydrophilic matrix in which the outer surface is modified to impart lipophilicity |
摘要 |
Vector (A), for oral administration of at least one pharmacologically active substance (I), that allows passage of (I) from the lumen of the intestines into the blood, optionally through interstitial fluid, without significant denaturation or degradation. (A) comprises an essentially hydrophilic matrix the outer surface of which is modified by one or more chemical species (II) that confer lipophilicity to (A). Independent claims are also included for the following: (1) gastric resistant vehicles (B) that comprise one or more (A); and (2) pharmaceutical composition containing at least one (A) or (B).
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申请公布号 |
FR2854072(A1) |
申请公布日期 |
2004.10.29 |
申请号 |
FR20030004976 |
申请日期 |
2003.04.23 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS |
发明人 |
FRERE YVES;DANICHER LOUIS;BELCOURT ALAIN |
分类号 |
A61K9/48;A61K9/51;A61K9/52;A61K38/28;A61P3/10;(IPC1-7):A61K9/48 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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