| 摘要 |
The present invention relates to a solid oral pharmaceutical composition in powder dosage form comprising
a) micronized omeprazole or an enantiomer thereof, including a pharmacologically suitable salt or other derivative thereof; and
b) a buffering agent which is sodium bicarbonate;
wherein the dosage form is not enteric coated and is devoid of any delayed-release or sustained-release delivery mechanism. Also provided is a method of making a liquid oral pharmaceutical composition, comprising contacting the powder with an aqueous diluent;
a kit comprising the pharmaceutical composition and a diluent; and
a pharmaceutical composition for use in the treatment or prevention of at least one gastrointestinal condition selected from the list consisting of active duodenal ulcers, gastric ulcers, dyspepsia, gastroesophageal reflux disease, severe erosive esophagitis, poorly resistant symptomatic gastroesophageal reflux disease and Zollinger Ellison syndrome. |
