发明名称 Preparation of soluble molecular complexes, useful for delivering e.g. pharmaceuticals, by molecular diffusion of active agents into host molecules in presence of diffusion agent
摘要 <p>Method for preparing soluble molecular complexes (A) that consist of at least one active substance (I), poorly soluble in aqueous medium, incorporated into one or more host molecules (II). (I) and (II) are mixed then subjected to a molecular diffusion step in which the mixture is contacted, in static mode, with a dense fluid (III) under pressure, in presence of at least one diffusion agent (IV), then (A) recovered. An independent claim is also included for (A) prepared by the new method.</p>
申请公布号 FR2854079(A1) 申请公布日期 2004.10.29
申请号 FR20030005140 申请日期 2003.04.25
申请人 PIERRE FABRE MEDICAMENT 发明人 LOCHARD HUBERT;SAUCEAU MARTIAL;FREISS BERNARD
分类号 A61K47/48;(IPC1-7):A61K47/40;A61K31/443;A61K31/506;A61K31/541;A61K31/381 主分类号 A61K47/48
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