发明名称 |
Antisense modulation of glycogen synthase kinase 3 alpha expression |
摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of glycogen synthase kinase 3 alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding glycogen synthase kinase 3 alpha. Methods of using these compounds for modulation of glycogen synthase kinase 3 alpha expression and for treatment of diseases associated with expression of glycogen synthase kinase 3 alpha are provided.</p> |
申请公布号 |
AU2001232814(B2) |
申请公布日期 |
2004.10.28 |
申请号 |
AU20010232814 |
申请日期 |
2001.01.16 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BRETT P MONIA;JACQUELINE R WYATT;MADELINE M. BUTLER;ROBERT MCKAY |
分类号 |
C07H21/04;A61K9/10;A61K31/711;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61P3/10;A61P7/00;A61P25/00;A61P35/00;A61P43/00;C12N15/113;(IPC1-7):A61K31/711;C12N5/06;C07H21/00 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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