发明名称 Crystal and process for producing the same
摘要 A process for producing crystals of 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimdazole-7-carboxylic acid (compound (I)), characterized by dissolving or suspending the compound (I) or a salt thereof in a solvent comprising an aprotic polar solvent and crystallizing it. By the process, the contaminants which are contained in the compound (I) or its salt and are difficult to remove, such as tin compounds, analogues of the compound (I), and a residual organic solvent, can be easily removed. Crystals of the compound (I) can be efficiently and easily mass-produced in high yield on an industrial scale.
申请公布号 US2004215023(A1) 申请公布日期 2004.10.28
申请号 US20040485593 申请日期 2004.02.02
申请人 HASHIMOTO HIDEO;MARUYAMA HIDEAKI 发明人 HASHIMOTO HIDEO;MARUYAMA HIDEAKI
分类号 A61P9/00;A61P9/12;A61P11/00;A61P13/12;A61P25/00;A61P29/00;A61P43/00;C07D403/10;(IPC1-7):C0743/02 主分类号 A61P9/00
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