发明名称 PREVENTIVE/REMEDY FOR RETINAL NERVE DISEASES CONTAINING ALKYL ETHER DERIVATIVES OR SALTS THEREOF
摘要 An alkyl ether derivative represented by the following general formula [1] o r its salt: wherein R1 and R2 represent each a substituent such as hydrogen, halogeno or alkyl; R3 represents alkylamino, amino or hydroxyl; the ring A represents a 5- or 6-membered aromatic heterocycle or a benzene ring; m and n are each an integer of from 1 to 6; and p is an integer of from 1 to 3; show s an effect of protecting retinal nerve cells and, therefore, is useful as a preventive and/or a remedy for retinal nerve diseases such as glaucoma, diabetic retinopathy, retinal artery obstruction, retinal venous obstruction , macular degeneration and retinopathy of prematurity.
申请公布号 CA2521648(A1) 申请公布日期 2004.10.28
申请号 CA20042521648 申请日期 2004.04.15
申请人 TOYAMA CHEMICAL CO. LTD. 发明人 KIMURA, TATSUO;SAITOH, AKIHITO;IWAKAMI, NOBORU
分类号 A61K31/397;A61K31/40;A61K31/4025;A61K31/435;A61K31/4525;A61K31/4535;A61P9/10;A61P27/02;C07D207/12;C07D405/12;C07D409/12;(IPC1-7):A61K31/397;C07D205/04;C07D207/10;C07D211/36;A61K31/402;A61K31/452;A61K31/453 主分类号 A61K31/397
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