Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine

摘要

The present invention provides compositions and methods for the treatment of migraine. More particularly, the invention provides a combination therapy for the treatment of migraine comprising the administration to a subject of a 5-HT1B/1D agonist in combination with a cyclooxygenase-2 selective inhibitor.