| 摘要 |
PROBLEM TO BE SOLVED: To provide a new pharmaceutical having RFRP receptor function regulating action. SOLUTION: An RFRP receptor function regulating agent contains a compound expressed by formula (I) äring A is an aromatic ring; X is a bond, O, NR<SP>4</SP>(R<SP>4</SP>is H, a hydrocarbon residue or a heterocyclic ring) or an alkylene; R<SP>1</SP>is a hydrocarbon residue or a heterocyclic ring; R<SP>2</SP>is -COYR<SP>5</SP>[Y is a bond, an alkylene, O, S or NR<SP>6</SP>(R<SP>6</SP>is H, a hydrocarbon residue or a heterocyclic ring); and R<SP>5</SP>is a hydrocarbon residue or a heterocyclic ring], a hydrocarbon residue or a heterocyclic ring; and R<SP>3</SP>is a hydrocarbon residue, a heterocyclic ring, a hydroxy which may be substituted, an amino which may be substituted or -S(O)<SB>n</SB>R<SP>7</SP>(R<SP>7</SP>is a hydrocarbon residue or a heterocyclic ring; and n is 0 to 2)}, its salt or its prodrug. COPYRIGHT: (C)2005,JPO&NCIPI
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