摘要 |
<p>Compounds of formula (I) are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation mediated by Bradykinin. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes wherein q, t, R, R<a>, R<b>, R<c> and R<2> are as defined herein.</p> |
申请人 |
AMGEN, INC.;ARRAY BIOPHARMA, INC.;GRONEBERG, ROBERT, D.;ZHAN, JAMES;ASKEW, BEN;D'AMICO, DERIN;HAN, NIANH;FOTSCH, CHRISTOPHER, H.;LIU, QINGLAN;RIAHI, BABAK;ZHU, JIAWANG;YANG, KEVIN;CHEN, JIAN, J.;NOMAK, RANA |
发明人 |
GRONEBERG, ROBERT, D.;ZHAN, JAMES;ASKEW, BEN;D'AMICO, DERIN;HAN, NIANH;FOTSCH, CHRISTOPHER, H.;LIU, QINGLAN;RIAHI, BABAK;ZHU, JIAWANG;YANG, KEVIN;CHEN, JIAN, J.;NOMAK, RANA |