发明名称 |
Medical devices and methods for inhibiting proliferation of smooth muscle cells |
摘要 |
The present invention provides HDAC inhibitors for use in inhibiting proliferation and/or migration of smooth muscle cells. The present invention further provides medical devices coated with the HDAC inhibitors. The present invention also provides use of the medical devices in methods for inhibiting proliferation and/or migration of smooth muscle cells. Additionally, the present invention provides methods for inhibiting proliferation and/or migration of non-neoplastic smooth muscle cells. Finally, the present invention provides methods for preventing or treating restenosis after angioplasty or stent implantation in a subject.
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申请公布号 |
US2004213826(A1) |
申请公布日期 |
2004.10.28 |
申请号 |
US20030425354 |
申请日期 |
2003.04.28 |
申请人 |
MARX STEVEN O.;MARKS ANDREW ROBERT |
发明人 |
MARX STEVEN O.;MARKS ANDREW ROBERT |
分类号 |
A61F2/958;A61K31/00;A61K31/165;A61K31/19;A61K38/15;A61L29/16;A61L31/16;(IPC1-7):A61K38/12 |
主分类号 |
A61F2/958 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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