发明名称 |
Prevention and treatment of Alzheimer amyloid deposition |
摘要 |
The present invention is directed to a method of preventing or treating Alzheimer's Disease or of inhibiting accumulation of amyloid-beta deposits in a subject by administering to the subject an agent which inhibits interaction between amyloid-beta and proteins which chaperone amyloid-beta under conditions effective to prevent or treat Alzheimer's Disease in the subject or to inhibit accumulation of amyloid-beta deposits in the subject's brain, respectively. Another embodiment of the present invention relates to a method of inhibiting interaction between apolipoprotein E and amyloid-beta by administering an agent which blocks interaction of apolipoprotein E and amyloid-beta under conditions effect to block such interaction.
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申请公布号 |
US2004214774(A1) |
申请公布日期 |
2004.10.28 |
申请号 |
US20040810919 |
申请日期 |
2004.03.26 |
申请人 |
WISNIEWSKI THOMAS;SADOWSKI MARCIN;SIGURDSSON EINAR M |
发明人 |
WISNIEWSKI THOMAS;SADOWSKI MARCIN;SIGURDSSON EINAR M |
分类号 |
A61K38/17;C07K;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/17 |
代理机构 |
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