IDENTIFICATION OF ORGANIC COMPOUNDS CAPABLE OF MODULATING THE ACTIVITY OF EPITHELIAL SODIUM ION CHANNELS
摘要
A method of identifying a substance that modulates the activity of epithelial sodium ion channels and as such may be suitable for use in the treatment of inflammatory diseases. The method involves treating a sample of epithelial cells with a candidate substance and a fluorescent membrane potential sensitive dye and measuring any changes in fluorescence.
申请公布号
WO2004072645(A3)
申请公布日期
2004.10.28
申请号
WO2004EP01371
申请日期
2004.02.13
申请人
NOVARTIS AG;NOVARTIS PHARMA GMBH;DANAHAY, HENRY, LUKE;GOSLING, MARTIN