发明名称 |
Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes |
摘要 |
An objective of the present invention is to provide a method for producing substance PF1022 derivatives, in particular PF1022-220 and PF1022-260, by a direct fermentation method, and a transformant to be used for this method. According to the present invention, there is provided a transformant producing substance PF1022 derivatives, which can be obtained by introducing a gene involved in a biosynthetic pathway from chorismic acid to p-aminophenylpyruvic acid into a phenylalanine auxotrophic host induced from an organism that produces a substance PF1022. According to the present invention, there is also provided a process of producing substance PF1022 derivatives, comprising steps of culturing the abovementioned transformant and collecting the substance PF1022 derivatives.
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申请公布号 |
US2004214274(A1) |
申请公布日期 |
2004.10.28 |
申请号 |
US20030472587 |
申请日期 |
2003.09.22 |
申请人 |
YANAI KOJI;SUMIDA NAOMI;WATANABE MANABU;MORIYA TAKATSUKI;MURAKAMI TAKESHI |
发明人 |
YANAI KOJI;SUMIDA NAOMI;WATANABE MANABU;MORIYA TAKATSUKI;MURAKAMI TAKESHI |
分类号 |
C12N1/15;C12N1/21;C12N15/52;C12N15/61;C12P17/14;(IPC1-7):C12P21/02;C07H21/04;C07K7/60 |
主分类号 |
C12N1/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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