发明名称 |
Peptide-based fluorescence polarization assay for detection of antibodies to mycobacterium bovis |
摘要 |
The present invention provides an assay for detection of M. bovis-infected animals. A tracer, comprising a peptide of M. bovis protein MPB70 conjugated to a fluorophore, is added to a serum sample from an animal to form a mixture. The fluorescence polarization of the mixture in then measured and compared to the fluorescence polarization of a control. The present invention further provides a tracer for use in fluorescence polarization assay to detect antibodies specific for M. bovis. The tracer comprises a peptide of M. bovis protein MPB70 conjugated to a fluorophore, such that the tracer is able to bind to antibodies specific for M. bovis to produce a detectable change in fluorescence polarization.
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申请公布号 |
US2004214250(A1) |
申请公布日期 |
2004.10.28 |
申请号 |
US20040492998 |
申请日期 |
2004.04.19 |
申请人 |
SURUJBALLI OM P;ROMANOWSKA ANNA;JOLLEY MICHAEL E;NASIR MOHAMMAD SARWAR |
发明人 |
SURUJBALLI OM P;ROMANOWSKA ANNA;JOLLEY MICHAEL E;NASIR MOHAMMAD SARWAR |
分类号 |
C07K14/35;G01N33/542;G01N33/569;(IPC1-7):G01N33/554 |
主分类号 |
C07K14/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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