SPIRO DERIVATIVE, PRODUCTION PROCESS, AND ANTIOXIDANT

摘要

A compound represented by the formula (1): (wherein R1, R2, and R3 each independently represents hydrogen or C1-8 alkyl; bond A-B represents the formula -CH2-CH2-, -CH=CH-, etc.; and X represents oxygen, sulfur, etc.) or a pharmaceutically acceptable salt thereof; and a process for producing the compound or salt. Also provided are: an antioxidant containing the compound as an active ingredient; and a therapeutic agent for kidney diseases or cerebrovascular disorders, a depressant for retinal oxidation disorders, and a lipoxygenase inhibitor which each comprises the antioxidant.